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甲磺酸伊马替尼新辅助治疗低位直肠恶性间质瘤效果观察 被引量:1

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摘要 目的 探讨甲磺酸伊马替尼新辅助治疗低位直肠恶性间质瘤的临床效果。方法 对应用甲磺酸伊马替尼新辅助治疗的中晚期低位直肠恶性间质瘤患者42例临床资料进行回顾性分析。结果 术前经新辅助治疗后临床完全缓解(CR)1例,部分缓解(PR)28例,稳定(SD)13例,有效率达76.2%(29/42),无肿瘤进展病例。化疗过程中未发现严重并发症。Ⅱb期患者新辅助治疗的有效率明显高于Ⅲa期和Ⅲb期患者(P〈0.05)。27例肿瘤切除患者均恢复良好,未见肿瘤转移病例。结论 甲磺酸伊马替尼新辅助治疗低位直肠恶性间质瘤效果显著,不良反应少,方便易行,值得临床推广。
出处 《中国基层医药》 CAS 2012年第12期1807-1808,共2页 Chinese Journal of Primary Medicine and Pharmacy
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