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肝静脉压力梯度对肝硬化门脉高压患者严重并发症的预测价值 被引量:5

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摘要 目的 研究肝硬化患者肝静脉压力梯度(HVPG)对肝癌、低钠血症的预测价值。方法 对170例肝炎肝硬化化患者的Child-Pugh评分、肝静脉压力梯度、肝癌和低钠血症发生率进行了系列的连续研究,随访时间(33.9±27.9)个月。结果 24例患者在随访过程中发生肝癌,多因素分析发现HVPG超过15 mm Hg则肝癌发生率明显增加(r=1.128,P〈0.05),Kaplan-Meier生存分析也发现HVPG与肝癌发生的时间长短有关。20例患者在随访过程中发生了低钠血症,多因素分析证实HVPG大于15 mm Hg低钠血症发生率明显升高(r=1.169,P〈0.05)并与低钠血症发生的时间有关。结论 在肝硬化患者中,HVPG可以作为预测肝癌、低钠血症及病症转归的一个重要指标。
出处 《中国基层医药》 CAS 2012年第12期1820-1822,共3页 Chinese Journal of Primary Medicine and Pharmacy
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