期刊文献+

氟伐他汀联用贝那普利对早期糖尿病肾病的疗效观察 被引量:4

下载PDF
导出
摘要 目的探讨氟伐他汀与贝那普利联用对早期糖尿病肾病(DN)的治疗效果。方法氟伐他汀组40例患者均单纯服用氟伐他汀,贝那普利组40例患者均单纯口服贝那普利,联合组40例采用二药联合用药。结果 3组治疗前UAER、CRP、Scr无显著差异(P>0.05),联合组用药1、2、3疗程后UAER、CRP、Scr均明显低于氟伐他汀组和贝那普利组,数据经统计学比较具有显著差异(P<0.05)。结论氟伐他汀与贝那普利联合应用治疗DN可有效改善患者肾功能,减少蛋白尿,且具有安全性。
出处 《海峡药学》 2012年第6期171-172,共2页 Strait Pharmaceutical Journal
  • 相关文献

参考文献5

二级参考文献15

  • 1李辉,李俭春,江时森,杜宏,顾小萍.卡托普利对糖尿病大鼠主动脉胶原非酶糖化的抑制作用[J].中国糖尿病杂志,1996,4(2):83-85. 被引量:15
  • 2杨霓芝,刘旭生.糖尿病肾病诊断、辨证分型及疗效评定标准(试行方案)[J].上海中医药杂志,2007,41(7):7-8. 被引量:1148
  • 3Barzilay J I,Abrham L,heckbert SR,et al.The relation of markers of inflammation to the development of glucose disorders in the elderly:the cardiovascular helth study[J].Diabetes,2001,50(10):2384.
  • 4Romano M, Pomilio M, Vigneri S, et al. Endothelial perturbation in children and adolescents with type 1 diabetes: association with markers of the inflammatory reaction[J]. Diabetes Care, 2001,24(9) : 1674.
  • 5Tsutomu H, Taro S, Gen Y, et al. Effect of simvatatin on apoprotein bcontaining lipoproteins in patients with diabetic nephropathy [ J ]. Curt Therap Res, 2002, 63(1):33.
  • 6Hostetter TH. Pathogenesis of diabetic glomerulopathy; hemodynamic considerations [ J ]. Semin Nephrol, 1990,11 ( 4 ) : 217.
  • 7Nieslsen S,Schmitz A,Rehling M,et al. Systolic blood pressure relates to the rate of deline of glomerular filtration rate in type Ⅱ diabetes mellitus[J]. Diabetologia,1993,16:1427.
  • 8Mogensen CE. Prevention and treatment of renal disease in insulindependent diabetes mellitus[J ]. Semin Nephrol, 1990,11 ( 1 ) : 23.
  • 9Zatz R,Meyer TW,Renneke HG,et al. Predominance of hemodynamie rather than & 127 ; metabolic factors in the pathogenesis of diabetic glomerulopathy[J ]. Proc Natl Acad Sci USA, 1985,82(17) :5963.
  • 10BUEMI M, ALLEGRA A, CORICA F, et al. Effect of fluvastation on proteinuria in patients with immunoglobulin A nephropathy[J].Clin Pharmacol Ther, 2000, 67(4): 427-431.

共引文献1157

同被引文献28

引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部