瑞芬太尼联合七氟烷对妇科腔镜手术患者应激反应的影响被引量：3

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摘要目的探讨瑞芬太尼联合七氟烷对全麻妇科腔镜手术应激反应效果及机制应的。方法 60例择期妇科手术患者,ASAⅠ~Ⅱ级,随机分为两组,每组30例。瑞芬太尼＋七氟烷组（R组）,芬太尼＋丙泊酚＋七氟烷组（B组）记录两组麻醉诱导前（T0）、插管后2min（T1）、术中1h（T2）、2h（T3）、手术结束（T4）及拔管后（T5）的血流动力学变化,记录HR,MAP,测定血糖,皮质醇,白介素-6（IL-6）水平;记录自主呼吸恢复时间,清醒时间及离开手术室时间。结果两组各时间点HR,MAP,测定血糖,皮质醇,白介素-6（IL-6）均有升高（P〈0.05）以（T1）（T2）（T3）明显R组各时间点与B组比较差异有统计学意义（P〈0.05）。结论瑞芬太尼联合七氟烷麻醉方法能明显减轻手术应激反应,维持术中血流动力学稳定,具有恢复时间短,质量高的优点。

作者丁梯杰金理照

机构地区浙江温州苍南县人民医院麻醉科

出处《海峡药学》 2012年第6期177-179,共3页 Strait Pharmaceutical Journal

关键词妇科腹腔镜瑞芬太尼七氟烷应激反应

分类号 R969.4 [医药卫生—药理学]

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