三叶鬼针草化学成分的研究

Study on the Chemical Constituents of Bidens pilosa

对产于广西靖西的三叶鬼针草全草的化学成分进行研究,采用硅胶柱层析、重结晶等分离手段从中分离纯化得到12个化合物,通过现代波谱技术和理化常数测定鉴定了它们的结构,分别为:金丝桃苷(hyperin 1),香豆素(coumarin 2),水扬酸(salicylic acid 3),5,7-二羟基色原酮(5,7-dihydroxychromone 4),1-苯基-1,3,5-三庚炔(1-phenylhepta-1,3,5-triyne 5),苯甲酸(benzoic acid 6),豆甾醇(stigmastero 7),十六烷酸(palnitic acid 8),十四烷酸(octaco-sane 9),二十八烷烃(octacosane 10),β-谷甾醇(β-sitosterol 11),胡萝卜苷(daucosterol 12),其中化合物4～10为首次从该植物中分离得到.

The chemical constituents of Bidens pilosa were studied and twelve compounds were isolated by silica column chromatography and recrystallization. The structures of the compounds were elucidated as hyperin （1）, coumarin （2）, salicylic acid （3）, 5,7 - dihydroxychromone （4）, 1 - phenylhepta - 1,3,5 - triyne （ 5 ）, benzoic acid （6）, stigmasterol （7）, palnitic acid （8）, octacosane （9）, octacosane （ 10）, β - sitosterol （ 11 ） and dau- costerol （12） by spectral analysis. Compounds 4--10 were isolated from this plant for the first time.