下腔静脉滤器置入预防肺动脉栓塞的生物相容性和安全性

Biocompatibility and safety of inferior vena cava filter implantation in preventing pulmonary embolism

背景:下腔静脉滤器应用于临床可预防肺动脉栓塞。目的:探讨下腔静脉滤器置入预防肺栓塞的生物相容性、安全性和手术适应证,以及相关并发症出现的原因与预防措施。方法:回顾性分析桂林市人民医院2001/2011经颈内静脉或股总静脉置入下腔静脉滤器治疗的下肢深静脉血栓96例患者临床资料。结果与结论:96例中55例置入永久性滤器,23例置入可回收滤器,18例置入临时性滤器。置入后随访8个月～7年,有症状的肺栓塞发生者1例,滤器倾斜2例,轻微宿主反应2例,均未对治疗有太大影响。表明下腔静脉滤器置入可以有效预防致命性肺栓塞,具有良好的生物相容性和安全性。

BACKGROUND： Inferior vena cava filter can prevent pulmonary embolism in clinical practice OBJECTIVE： To explore the biocompatibility, safety, surgical indications, and causes and preventive measures of related complications of inferior vena cava filter implantation in preventing pulmonary embolism. METHODS： A retrospective analysis was performed in 96 patients in the People＇s Hospital of Guilin from 2001 to 2011 receiving vena cava filter implantation for treatment of deep venous thrombosis. RESULTS AND CONCLUSION： Fifty-five patients were implanted with permanent filter, 23 cases were implanted with recyclable filter, and 18 patients were with temporary filter. All the patients were followed up for 8 months to 7 years. Pulmonary embolism occurred in one patient, filter tilting happened in two cases, and slight host response could be seen in one case, all of the above did not influence the treatment. It is indicated that inferior vena cava filter can efficiently prevent pulmonary embolism in clinical practice with good biocompatibility and safety.