摘要
目的:研究抗核抗体(ANA)与不同自身免疫性疾病的相关性。方法:选取近期入我院就诊的自身免疫性疾病患者104例,对其血清进行ANA检测。观察不同自身免疫性疾病与ANA阳性率,荧光核型模型的相关性。结果:104例患者中,ANA阳性为95例,阳性率为91.3%。系统性红斑狼疮(SLE)、干燥综合征(SS)、类风湿关节炎(RA)、系统性硬化症(SSc)、强制性脊柱炎(AS)的阳性率分别为98.1%、75.0%、88.9%、85.7%、80.0%。SLE、SS、RA的ANA荧光核型模型结果以颗粒型为主,AS无占主导的荧光核型。结论:不同自身免疫性疾病患者的ANA阳性率不同。荧光核型模型可辅助判定靶向抗原,但并不绝对。
Objective： To study the correlation between antinuclear antibody （ANA） and autoimmune diseases （AID）. Methods： Choosed 104 AID patients to detect ANA. Observed positive rate of ANA and correlation with fluorescence karyotype model in different AID. Results： The positive rate of ANA was 91.3%,and the positive rate of SLE, SS, RA, SSc and AS separately were 98.1%, 75.0%, 88.9%, 85.7%, 80.0%. The fluorescence karyotype model of SLE, SS, RA was spot-type, while there no lead fluorescence karyotype in AS. Conclusion： The positive rate of ANA in different AID was diverse. The fluorescence karyotype model could determine target antigen auxiliarily but not absolutely.
出处
《求医问药（下半月刊）》
2012年第4期204-204,共1页
Seek Medical and Ask The Medicine
关键词
抗核抗体
自身免疫性疾病
荧光核型模型
antinuclear antibody
autoimmune diseases
fluorescence karyotype model
