栾树种子的化学成分研究

CHEMICAL CONSTITUENTS FROM THE SEEDS OF KOELREUTERIA PANICULATA LAXM

目的 :分离鉴定栾树 (KoelreuteriapaniculataLaxm .)种子的化学成分。方法 :分别用石油醚回流提取和95 %EtOH浸提 ,硅胶柱色谱分离 ,IR ,MS ,UV ,1HNMR ,13 CNMR等方法确定结构。结果 :分得 8个化合物 ,分别为3 O 十四烷酰基 1 腈基 2 甲基 1,2 丙烯 (1) ,3 O 二十碳 14,15 烯酰基 1 腈基 2 甲基 1,2 丙烯 (2 ) ,3 O 二十碳 14,15 烯酰基 4 O 十八烷酰基 1 腈基 2 氧代亚甲基 1,2 丙烯 (3) ,3 O (6′ 亚油酰基 葡萄糖 ) β 谷甾醇 (4) ,1 O β D 葡萄糖 2 O 油酸 3 O 十六烷酸甘油酯 (5 ) ,1 O 十六烷酸甘油酯 (6 ) ,14,15 二十碳烯酸 (7) ,三油酸甘油酯(8)。结论 :1～ 3为新化合物 ,4～ 8系首次从该植物中分得 ,并归属其波谱信号。

AIM: Isolation and structural elucidation of the seeds of the Chinese medicinal plant Koelreuteria paniculata Laxm. METHODS: The seeds were extracted with petroleum ether by percolation and the crude extracts were purified by using silica gel chromatography. IR,UV,MS, 1H and 13 CNMR spectra were employed for structural identification. RESULTS: Eight compounds named 3 O tetradecanoyl 1 cyano 2 methyl 1,2 propene(1), 3 O 14,15 eicosylenoyl 1 cyano 2 methyl 1,2 propene(2) and 3 O 14,15 eicosylenoyl 4 O stearoyl 1 cyano 2 oxymethyl 1,2 propene(3), 3 O ( linoleicoyl β D glycopyranoside) β sitosterol(4), 1 O β D glycopyrano 2 O oleo 3 O hexadecanolenin(5), 1 O hexadecanolenin(6), 14,15 eicosenic acid(7), triolein(8) were isolated. CONCLUSION: Three new compounds in term of 3 O tetradecanoyl 1 cyano 2 methyl 1,2 propene(1), 3 O 14,15 eicosylenoyl 1 cyano 2 methyl 1,2 propene(2) and 3 O 14,15 eicosylenoyl 4 O stearoyl 1 cyano 2 oxymethyl 1,2 propene(3), together with four other compounds were isolated from the seeds, and compounds 4～7 were obtained from this plant for the first time.