局限性膀胱淀粉样变1例报告并文献复习

Localized amyloidosis of the urinary bladder: A case report and review of literature

目的:探讨局限性膀胱淀粉样变病因、临床表现、影像学诊断方法、病理特征及诊疗方法。方法:回顾分析1例局限性膀胱淀粉样变患者的临床资料,总结复习相关文献。结果:患者经抗感染、止血、对症治疗,效果较好,随访7个月未复发血尿。结论:膀胱淀粉样变为少见病,主要表现为无痛性肉眼血尿,膀胱侧壁和三角区为好发部位,确诊主要依靠膀胱镜下活检,病理学检查刚果红染色后偏振光显微镜下呈现出苹果绿色双折射光。治疗以手术切除为主,术后辅以二甲基亚砜膀胱灌注,疗效及预后良好。

Objective.. To detect the etiopathogenisis, clinical, radiological, pathological characteristics, diagnostic and therapic methods of localized amyloidosis of the urinary bladder. Method：The clinical and pathological data of one case of localized urinary bladder amyloidosis was retrospectively analysed. And we reviewed and sum- marized literatures. Result：The patient recovered though the treatment of anti-inflammatory hemostasis and symptomatic treatment, and hematuria did not recur within 7 months. Conclusion： Localized amyloidosis of the urinary bladder is a rare disease which manifested painless gross hematuria usually. The lateral wall and trigone of the bladder are commonly affected areas. Definitive diagnosis rested on examination of a biopsy specimen and Congo red dye. The prognosis is good after the treatments of trans-urethral resection and supplemented with intravesical DMSO instillation.