多聚腺苷酸二磷酸核糖转移酶抑制剂的放射增敏作用及机制研究
摘要
放疗是恶性肿瘤的主要治疗手段之一,临床上约70%的恶性肿瘤患者在治疗不同阶段需接受放疗。多种细胞毒药物被用于放疗联合治疗以增加对肿瘤的治疗疗效,如氟尿嘧啶、顺铂、卡铂和丝链霉素C等,然而它们往往在增加肿瘤细胞杀伤的同时也加重了正常组织损伤,因此寻找特异性针对肿瘤的放射增敏剂是放疗研究的方向。
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2012年第4期380-383,共4页
Chinese Journal of Radiation Oncology
基金
国家自然科学基金项目(81072164)
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