不同手术策略治疗岛叶胶质瘤的效果分析

The effect analysis of different strategies for the surgery of insular glioma

目的对比研究常规显微手术、神经功能导航辅助手术以及术中核磁辅助手术对岛叶胶质瘤治疗的效果。方法回顾性分析2007年3月至2011年3月在解放军总医院神经外科手术治疗89例岛叶胶质瘤患者的临床资料,比较常规显微手术(常规组)、神经功能导航辅助手术(导航组)、术中核磁辅助手术(核磁组)切除程度与术后功能障碍发生率。结果常规组、导航组与核磁组全切率分别为47.4%、66.7%、80.8%,术后发生早期神经功能障碍分别为42.1%、38.9%、38.4%,发生永久性神经功能障碍分别为21.0%、11.1%、7.6%。结论岛叶胶质瘤手术治疗以术中核磁辅助手术较常规显微手术及神经功能导航辅助手术效果更佳。

Objective To compare the efficacy of intraoperative MRI guided surgery, neuro-navigation guided surgery and conventional mireosurgery as they were applied to patients with Insular glioma. Methods Eighty-nine cases of InsUlar glioma in our department from March 2007 to March 2011 were retrospectively analyzed, and the main targets are the extent of resection and neurologic deficits. Results The percentage of total resection were 47.4% in conventional group,66.7% in neuro navigation group, 80.8% in IMRI group. Postoperative neurologic deficits for the three groups were 42.1%,38.9% and 38.4% respectively. Long term neurologic deficits for the three groups were 21.0%, 11.1% and 7.6% respectively. Conclusions Intraoperative MRI-assisted surgery is more effective than the past assisted techniques for the treatment of insular gliomas.