雾化吸入硝酸甘油治疗先天性心脏病合并肺动脉高压的护理观察

Clinical observation of nitroglycerin aerosol inhalation treating congenital heart disease with pulmonary hypertension

目的:探讨雾化吸入硝酸甘油治疗先天性心脏病合并继发性肺动脉高压的护理观察。方法:将我科2006年6月～2011年6月收治的465例先天性心脏病合并不同程度肺动脉高压的患者随机分为两组,治疗组采用硝酸甘油雾化吸入,对照组采用常规治疗。两组治疗1周后,比较两组患者肺动脉平均压、体外循环后呼吸机辅助时间、术后氧分压(PO2)情况。结果:治疗组肺动脉压控制情况较对照组明显有效,两组比较有统计学差异(P<0.05)。结论:硝酸甘油雾化吸入用于先天性心脏病合并肺动脉高压的干预治疗,能取得较好的治疗效果及预期指标。

Objective： To explore the effect of Nitroglycerin aerosol inhalation treating secondary pulmonary hypertension which by congenital heart disease.Methods Analyse 465 patients who suffered congenital heart disease with pulmonary hypertension from June 2006 to June 2011,randomly divided into two group.Experimental group which treated with nitroglycerin aerosol inhalation,control group which treated with routine therapy.1 week later,Evaluated the quantity of mean pulmonary artery pressure（MPAP）,time of assistedrespiration after extracorporeal circulation,PO2 after operation.effective sputum culture results of the two groups patients.Results： Experimental group had significantly controlled PAP than control group.The results was significantly different between two groups（P0.05）.Conclusion：The method of nitroglycerin aerosol inhalation treating secondary pulmonary hypertension which by congenital heart disease could get better therapeutic efficacy and anticipative purpose,so that could be applied widely in the clinical practice.