成人经皮球囊肺动脉瓣成形术的临床应用

THE CLINICAL EFFECTS OF PERCUTANEOUS BALLOON PULMONARY VALVULOPLASTY IN ADULTS

目的：评价成人经皮球囊肺动脉瓣成形术（ＰＢＰＶ）临床应用的疗效。方法：采用 ＰＢＰＶ对 ３７例成人先天性肺动脉瓣狭窄患者进行治疗。结果：ＰＢＰＶ后即刻肺动脉瓣跨瓣压差（△Ｐ）由术前８１±２６ｍｍＨｇ降至３６±１７ｍｍＨｇ（Ｐ＜０．０１），３２例随访１～９年，平均４．３±２．１年，△Ｐ进一步降为２５±７ｍｍＨｇ。术中及术后无严重并发症。结论：ＰＢＰＶ治疗成人肺动脉瓣狭窄安全、有效，即刻与中远期效果均良好。

Objective: To evaluate the clinical effect percutaneous balloon pulmonary valvuloplasty (PBPV) in adults. Methods: PBPV for congenital pulmonary valve stenosis in adults was performed in 37 patients between 1988 and 1998, mean age was 27.1 years. Results: The systolic gradien(△p) from right ventricular to pulmonary artery was reduced from 81±26 mmHg to 36±17 mmHg immediately after PBPV(P<0.01). 32 patients had a follow-up 1-9 years (mean 4.3±2.1 years), and the △P was reduced progressively to 25±7 mmHg. Conclusion: Thus balloon pulmonary valvuloplasty is a safe and effective procedure for the treatment of patients with pulmonary valve stenosis in adults, and the late results of this procedure are as good as early results.