支气管肺神经内分泌肿瘤的特征及预后探析

Analysis of the characteristics and prognosis of bronchopulmonary neuroendocrine tumors.

目的探讨支气管肺神经内分泌肿瘤的临床特征,分析其预后。方法对本院2001年1月～2007年12月收治的84例支气管肺神经内分泌肿瘤患者的资料进行回顾性分析,总结患者的临床症状、影像学特征及患者的预后,对比不同年龄、性别、吸烟史、饮酒史、治疗方式与患者预后的相关性。结果 84例患者临床特征均不明显;其影像学检查根据患者的癌肿类型(大细胞癌、小细胞癌、典型类癌及非典型类癌)临床表现各不相同。患者1年生存率较高,达88.09%(74/84),其中以典型类癌的生存率最高。年龄、性别和吸烟史及家族史均与患者的预后无明显的相关性,而患者治疗方式与患者癌症类型与预后有一定的相关性。结论支气管肺神经内分泌肿瘤的临床症状不明显,其需要给予多种方式联合诊断,以病理结果作为金标准,患者的预后与多种因素均有明显的相关性。

Objective To investigate the clinical features and prognostic lactors ot bronchopulmonary neuroenoocnne tu- mors. Methods The data of 84 patients with bronchopulmonary neuroendocrine tumors collected from January 2001 to De- cember 2007 in our hospital were retrospectively analyzed. The clinical symptoms, imaging characteristics and prognosis were Summaried, the relation of the age, gender, smoking history, drinking history, treatment with the prognosis of the pa- tients were analysed. Results The clinical features were not obvious in 84 patients; imaging features were different, based on the patient＇s cancer type （large cell carcinoma, small cell carcinoma, typical kind of cancer and the typical kind of can- cer. 1-year survival rate of patients was higher and was up to 88.09% （74/84）, of which the highest survival rate was atypi- cal careinoid. Age, gender and smoking history and family history was no obvious correlation with the prognosis of patients, the treatment of patients was correlated with prognosis of patients. Conclusion The clinical symptoms of bronchopulmonary neuroendocrine tumors is not obvious, it needs to be given a variety of joint for the diagnosis, and pathological findings can be used as the gold standard, the prognosis of patients is significantly related with a variety of factors.