乳腺结构不良症囊性增生期诊疗探讨(附76例报告)

Investigation in diagnosis and therapy on cystic hyperplasia of mammary dysplasia:a report of 76 cases

目的 探讨乳腺结构不良症囊性增生期的临床诊断标准及治疗原则。方法 回顾性分析 76例囊肿增生病例。结果 76例中 ,有 8例重度不典型增生 ,6例乳头状瘤样增生 ,4例腺管型腺病 ,其它仅上皮增生。 1例腺瘤样增生肿块切除 ,10年后有恶变现象。结论 乳腺结构不良症的囊性增生期 ,临床诊断标准关键在于发病年龄为 40岁左右及无规律性乳痛 ,一侧肿块 ,组织学为导管上皮不典型增生为特点而决定诊治原则。为防止恶变及恶性病变漏诊 ,肿块切除后必须作常规病理检查。

Objecitve\ To study the principle of clinical diagnosis and therapy of cystic hyperplasia of mammary dysplasia.Methods\ Among 196 patients suffering from mammary dysplasia collected from 1986 to 1996 in Department of Surgery,The First Teaching Hospital of Henan Medical University,totally 76 cases were diagnosed as cystic hyperplasia of mammary dysplasia.A retrospective analysis of clinical characteristics and therapeutic methods was evaluated.Results\ Among 76 cases there were 8 cases of severe atypical hyperplasia,6 cases of papillary hyperplasia,4 cases of tubular adenosis and others were simple hyperplasia.Only one case of adenosis showed malignant change 10 years after operation.Conclusion\ The keys of clinical diagnosis are prevalence age,which is about 40 years old,irregular mastodynia and unilateral mass.Atypical dysplasia of ductal epithelium comfirmed by histology may determine the principle of diagnosis and therapy.It is necessary to make routine pathologic examination to prevent malignant change and missing diagnosis.