摘要
目的 探讨居住城市社区的农村老年患者认知功能障碍发生的危险因素。方法通过简易智力状态检查表(MMSE)对118例老年患者的认知功能进行评价,收集患者的一般资料,调查是否合并冠心病、高血压病、糖尿病、脑卒中、慢性阻塞性肺疾病,收集患者的血清低密度脂蛋白胆固醇(LDL—C)、同型半胱氨酸(Hcy)等资料并进行分析。结果118例患者中有17例出现不同程度的认知功能障碍,认知障碍的发生率为14.4%;单因素回归分析显示年龄、脑卒中病史、Hcy、LDL-C与智力状态检查结果呈相关性(X2=21.166、19.323、13.672、3.698,P〈0.01或P〈0.05);性别、配偶是否健在、高血压病、冠心病、糖尿病、慢性阻塞性肺疾病等因素均与卒中后认知功能障碍不相关(P〉0.05)。多因素回归分析显示,年龄(OR=0.853,95%CI:0.765~0.951)、脑卒中病史(OR=0.764,95%CI:0.629~0.929)、LDL厂C(OR=0.208,95%CI:0.062~0.701)和日常生活能力评分(ADL)(OR=0.839,95%CI:0.725~0.972)是老年患者认知功能障碍的独立危险因素。结论年龄、脑卒中病史、低密度脂蛋白胆固醇和日常生活能力是居住城市社区的农村老年患者认知功能障碍的独立危险因素。
Objective To explore the risk factors of cognitive impairment in rural elderly patients from Changzhi urban. Methods Totally 118 elderly patients were examined with minimental state examination (MMSE). The common data and histories of coronary heart disease, hypertension, diabetes and chronic obstructive pulmonary disease were collected. Results The prevalence of cognitive impairment was 14.4%. Multivariate analysis showed that MMSE scores was associated with age, stroke history, homocysteine and low density lipoprotein(LDL-C) (X2= 21. 166, 19. 323, 13. 672, 3. 698, P〈0.01 or P〈 0.05), and cognitive impairment was not associated with gender, alive spouse, hypertension, coronary heart disease, diabetes and chronic obstructive pulmonary disease(P〈0.05). Age(OR=0. 853,95% CI:0. 765-0. 951), stroke history(OR=0. 764, 95 % CI: 0. 629-0. 929), LDL-C (OR = 0. 208, 95 % CI: 0. 062-0. 701 ) and activities of daily living (ADL) (OR=0. 839,95% CI. 0 .725-0. 972) were independent risk factors of cognitive impairment in rural elderly patients. Conclusions Age, stroke and LDL-C are independent risk factors for rural elderly patients in the community.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2012年第7期623-625,共3页
Chinese Journal of Geriatrics
关键词
认知障碍
危险因素
农村卫生
Cognition disorders
Risk factors
Rural health