摘要
目的观察调中颗粒治疗功能性消化不良的临床治疗效果。方法根据功能性消化不良的罗马Ⅲ标准,选择功能性消化不良患者306例,随机分为两组,治疗组予调中颗粒,对照组予莫沙比利片,两组疗程均为4周。结果治疗组、对照组临床疗效总有效率分别为90.85%和70.59%,组间临床疗效比较,差异有统计学意义(P<0.05)。治疗组胃动素及胃泌素水平较前升高明显,与对照组相比差异有统计学意义(P<0.05)。两组治疗期间均未发生不良事件。结论调中颗粒比莫沙比利能更显著缓解功能性消化不良患者的临床症状,可能是通过对胃动素和胃泌素水平的影响而达到治疗目的。
Objective To observe the clinical effect of “Tiao zhong grain” in the treating of functional dyspepsia. Methods Three hundred and six cases of functional dyspepsia were randomly divided into 2 group. Treatment group were administered with “Tiao zbong grain”. One hundred and fifty - three cases in control group were administred with Mosapride three times before meal each day. Both groups were under treatment for four weeks. Before and after treatment, the efficiency were observed through the PAGI - SYMsymptom rating scale motilin, gastrin and gastric emptying. Results After treatment, the total effective rates in treatment group and control group were 90. 85% and 70. 59% ,The better improvement in treatment group than in control group( P 〈 0. 05 ). Compared with the control group, the treatment group had significant improvement in motilin gastrin and gastric emptying( P 〈 0. 05 ). No adverse events were found in both groups. Conclusions “Tiao zhong grain” can relieve clinical symptoms significantly better than Mosapride and likely to improve the motilin 、gastrin and gastric emp- tying by influencing the gastrointestinal hormone level.
出处
《湖北中医药大学学报》
2012年第3期17-19,共3页
Journal of Hubei University of Chinese Medicine