摘要
The ring opening reaction of methyloxirane(PO) in hydrochloric acid(HCl) has been studied by NMR and gas chromatography. It is found that under experimental conditions α and β chloropropanol in the reaction products were in a molar ratio of about 2∶1. The ratio was almost constant when the molar ratio of c PO ∶c HCl ranged from 1∶0 3 to 1∶1 4, at reaction temperature from 0 to 65 ℃ and reaction time from 1 to 60 min. It is proposed that the addition reaction of HCl should follow an S N2 mechanism, and that which carbon atom would be attacked by nucleophilic agent Cl - is decided by space factor and not by the electron factor.
The ring opening reaction of methyloxirane(PO) in hydrochloric acid(HCl) has been studied by NMR and gas chromatography. It is found that under experimental conditions α and β chloropropanol in the reaction products were in a molar ratio of about 2∶1. The ratio was almost constant when the molar ratio of c PO ∶c HCl ranged from 1∶0 3 to 1∶1 4, at reaction temperature from 0 to 65 ℃ and reaction time from 1 to 60 min. It is proposed that the addition reaction of HCl should follow an S N2 mechanism, and that which carbon atom would be attacked by nucleophilic agent Cl - is decided by space factor and not by the electron factor.
出处
《应用化学》
CAS
CSCD
北大核心
2000年第2期214-216,共3页
Chinese Journal of Applied Chemistry
基金
中国科学技术大学基地建设基金
鲁北化工企业集团总公司基金资助课题
