摘要
全反射荧光分析 (TXRF)比常规荧光分析 (XRF)具有更高的灵敏度。我们在北京正负电子对撞机同步辐射 3W 1A新光束线改建的同步辐射荧光站上 (更换了新探测器及相应谱仪系统 ) ,用TXRF对肺癌细胞和宫颈癌细胞进行了凋亡前后的研究 ,得到了这些细胞凋亡前后的荧光谱。从分析这些谱的结果我们可以看到 ,凋亡前后这些癌细胞中某些微量元素的含量有了变化 ,甚至是明显变化。从这些变化中我们可得到一些启发 ,如果能找到它们的变化规律是否可为治疗癌症做出一点贡献呢 ?
The sensitivity of total reflection X ray fluorescence analysis (TXRF) is higher than normal X ray fluorescence analysis (XRF).The cells of lung cancer and cervix cancer were researched before apoptosis and after apoptosis employed the method of TXRF on new transformed synchrotron radiation XRF experimental station of new 3W1A beam line which built on Beijing Synchrotron Radiation Facility (BSRF) of BEPC (new detector and spectrometer systems).We acquired their fluorescence spectrum of various elements before apoptosis and after apoptosis.We discovered there were interesting results that changes even remarkable changes of some elemental contents had occurred in these cells before apoptosis and after apoptosis.These alterations of elemental contents have served an inspiration for us:if their regularities of change are found,we will hope that some contributions would be done at the treatments of cancer.
出处
《光谱学与光谱分析》
SCIE
EI
CAS
CSCD
北大核心
2000年第2期240-242,共3页
Spectroscopy and Spectral Analysis
关键词
肺癌
宫颈癌
TXRF
癌细胞
凋亡
微量元素
Synchrotron radiation, TXRF, Cancerous cells apoptosis, Trace elements