肾上腺皮质激素治疗重肝倾向型肝炎的有效性和安全性分析

The Adrenal Cortical Hormone Treatment of Severe Liver Tendency Hepatitis Efficacy and SafetyAnalysis

目的:探讨肾上腺皮质激素治疗重型肝炎的有效性及不良反应。方法:将我院68例重肝倾向型肝炎的患者随机分为两组,对照组患者给予常规药物治疗,实验组患者在对照组患者治疗的基础上给予肾上腺皮质激素—地塞米松治疗,比较两组患者治疗4周后的肝功能能水平。结果:68例患者经过治疗均有好转,实验组患者的TBIL低于对照组患者,ALT、ALB和PTA均高于对照组患者,组间比较差异十分明显,P<0.05,差异有统计学意义。结论:使用肾上腺皮质激素有助于提高重型肝炎患者的治疗效果,医生在治疗时要重视对患者不良反应的观察。

Objective：To investigate the effectiveness and adverse reactions of the adrenal cortex hormone therapy of severe hepatitis.Methods：68 cases of severe hepatitis patients were randomly divided into two groups,control group,patients treated with conventional drug treatment,experimental group patients in the control group patients on the basis of given adrenal cortex hormone dexamethasone treatment were compared to the level of liver function in patients after 4 weeks.Results：68 patients have been treated better,the experimental group of patients with TBIL lower than control group patients,ALT,ALB and PTA were higher in patients between the two groups is very obvious difference,P〈0.05,statistically significant differences.Conclusion：The use of adrenal cortical hormone to help improve the treatment of patients with fulminant hepatitis,the doctor should pay attention to the treatment of patients with adverse reactions observed.