系统性红斑狼疮急症的临床研究

Clinical study of systemic lupus erythematosus in emergencies

目的:对系统性红斑狼疮(SLE)急症患者临床表现进行统计分析,为及时诊断及时治疗改善预后提供临床资料。方法:采用回顾性分析的方法对急诊121例SLE急症患者年龄、性别、病程、主诉症状、发热病因分析、受累系统种类及个数、预后等方面进行统计分析。结果:SLE急症在发病年龄,性别,主诉症状,发热病因分析,受累系统,预后等方面有明显特征性。结论:育龄期女性出现多系统损害或条件致病菌感染或不明原因发热要考虑SLE可能,复发狼疮伴有肾损害继发感染的患者预后差。

Objective：To statistically analyze the clinical presentations of patients with Systemic Lupus Erythematosis （SLE） in emergency department （ED）. Method： 121 patients with SLE who presented to the ED in emergency situation were retrospectively analyzed. Clinical data queried included： patient age, gender, duration of dis- ease, chief complaint in the ED, the causes of fever, the number and types of organ system involvement, and final outcome after ED management. Result： We found patients with SLE had different features in age, gender, chief complaint, the causes of fever, organ system involvement and prognosis. Conclusion： Women of childbearing age who have multi-system organ damage, opportunistic infections or fever of unknown origin should be considered for the diagnosis of SLE. Patients with recurrent SLE exacerbations accompanied by renal insufficiency and/or sec- ondary infection had worse prognosis.