2010年郑州市儿童医院轻重症手足口病患儿流行病学分析

Epidemiological analysis of HFMD patients hospitalized children with severe light In Zhengzhou children hospital in 2010

目的了解郑州及周边地区住院轻重症手足口病病例流行病学特征及其对比情况,掌握其流行规律,为防治提供依据。方法应用描述性流行病学方法及卡方检验进行分析。结果住院轻症手足口病病例以5～7月份发病率最高,郑州市各县(市)区病例数占66.4%,以4岁以下发病率最高,男女比1.57∶1;住院重症病例以3～8月份发病率最高,男女比1.73∶1,郑州市各县(市)区病例数占71.4%,以3岁以下发病率最高,PE和EV71混合阳性率最高为66.3%,占总阳性数的82.8%。住院手足口病病例1～2岁年龄组发病数最多为615例,占44.4%。结论住院重症病例发病高峰年龄较轻症患儿普遍小1岁左右,发病季节较轻症患儿较早,且持续时间长,男孩发病多于女孩,其中1～2岁年龄段是轻重症手足口病病例共同发病高峰。住院重症手足口病病例主要病原体是EV71型,且多与PE型病原体混合性感染。

Objective Understand the light of severe HFMD patients hospitalized children in Zhengzhou City and surrounding areas, the comparison of epidemiological characteristics and to master its popular rule, provide the basis for the prevention and treatment. Methods The descriptive epidemiological methods and chi-square test for analysis. Results Hospitalized children with mild HFMD patients the highest incidence of 5~7 months, Zhengzhou City, county （city） area accounted for 66.4 % of cases, with the highest incidence of 4 years of age, male to female ratio 1.57：1; hospitalized and critically ill patients with severe 3-8 months in children with the highest incidence of male to female ratio 1.73：1, Zhengzhou City, county （city） area accounted for 71.4 % of cas- es, with the highest incidence of under 3 years old, enterovirus 71 （EV71）Other enteric viruses （PE）mixed-positive rate of up to 66.3 %, 82.8 % of the total number of positive. Light of severe HFMD patients hospitalized children 1-2-year-old age group, inci- dence of up to 615 cases, accounting for 44.4 %. Conclusion Critically ill patient with severe disease in children younger age at disease onset of the peak about 1 year old children generally small, the incidence of disease in children less seasons earlier and last- ed longer, the incidence of boys more than girls, which is the age group 1-2 child patients with HFMD light of severe joint disease peak. Critically ill patients hospitalized with severe hand, foot and mouth disease is a major pathogen of children EV71 type, and more mixed with PE-type pathogen infection.