乙肝康治疗HBV感染的疗效观察

Curative effects of YIGANKANG on HBV infection

探讨乙肝康对HBV感染治疗效果。应用乙肝康治疗慢性乙肝感染 (包括慢性乙型病毒肝炎 ,乙型肝炎病毒携带者 ) 32例 ,同时随机设对照组 30例。治疗组给予乙肝康注射液 5毫升静点。每日一次 ,同时口服乙肝康 5粒 ,一日三次。对照组给猪苓多糖注射液 40毫克 ,肌注 ,连用 2 0日 ,停 10日 ,重复使用 3次 ,同时每 15日肌注乙肝疫苗 30微克 ,均为 3个月一个疗程。乙型肝炎病毒标志物的变化为考核依据。治疗组有 13例HBsAg阴性 ,转阴率为 40 6 % (13/ 32 ) ,7例抗HBe阳转。阳转率为 2 3 3% (7/ 32 ) ,有 12例HBVDNA阴转 ,阴转率为 37 5 % (12 / 32 ) ,与对照组比较差异明显。证明乙肝康对HBV标志物有较好的抑制作用。对消除HBsAg携带者具有较好的疗效 ,与干扰素抗乙肝病毒疗效相近似 ,且价格廉 ,无明显毒副作用 。

WT5”BZ]To search out the curative effectas of YIGANKANG on HBV infection our department have used YIGANKANG to treat chronic HBV infection since 1985(such as chronic HBV hepatitis,chronic HBV carrier without symptom) we casually selectsd 32 patients as a treatment group was treated by injecting YIGANKANG(5ml,qd,iv),and 5pills of YIGANKANG(tid,po);the comparing group was treated by injecting plyprous umbellatus polysaccharide(40mg,qd,im)for 20 days,then stop for 10 day This usage was repeated for 3 months as a curative period Curative effects were judged by the changes of HBV signing matenrial treatment group:HBsAg-negative 40 6%(13/32);Anti-HBe changed to be positive (7 cases) 37 5%(12/32) All changes were obviously different from the comparing group It was proved that YIGANKANG can inhibit HBV signing naterial and eliminate HBsAg infection effciently YIGAKANG has a low price and has no side and toxic effects,it can match interferon which was admitted by common consent in the world,it is suitable for spreading in China [WT5”HZ]