急性重症胆管炎导致多脏器功能障碍相关因素的探讨

Approach of related factor for Muitiple Organ Dysfunction

目的 :探讨急性重症胆管炎 (ACST)并多脏器功能障碍 (MODS)的临床特点及与之有关的重要因素 ,并对多脏器功能障碍的防治进行探讨。方法 :通过对 37例急性重症胆管炎患者的回顾性研究 ,分析多脏器功能障碍的发生率与死亡率、脏器衰竭数与死亡率的关系。结果 :MODS与 ACST关系密切 ,其中肝脏功能不全发生率最高 ,急性呼吸功能衰竭与急性肾功能衰竭是患者死亡的主要原因。脏器功能障碍个数越多死亡率越高。结论 :对于 ACST后并发 MODS,关键在于早期引流胆道 ,积极抗感染治疗 ,并及早对心、肺。

Objective:To study the clinic behavior and related factors of Acute Cholangitis of Severe Type combined with Multiple Organ Dysfunction Syndrome.Method:By retrospective study for total 37 patients with Acute Cholangitis of Severe Type,the relationship between incidence and mortality multiple organ dysfunction,and the relationship between quantity of exhausted organ and mortality had been analyzed.Results:There was a close relationship between MODS and ACST.Among these,incidence of liver malfunction was the highest and acute respiratory failure and acute renal function failure were the major causes of death.The more quantities of organ dysfunction,the higher of mortality.Conclusion:To MODS due to ACST,drainage of the bile duct in earlier period,treatment of anti infection and monitoring the major organs such as heart,lung and kidney are very important.