呈现多发性结节性损害的三期梅毒1例

A case of tertiary syphilis presented multiple nodular lesions

患者男 ,40岁 ,全身出现蚕豆大多发性结节 2年余 ,近 10日部分结节破溃 ,伴微热。组织病理显示附属器周围和皮下脂肪小叶内可见局限性上皮样细胞肉芽肿。USR ( 1∶3 2 )、RPR( 1∶16)、TPHA( 1∶160 )均为阳性。经用美洛西林 4g/d注射、阿奇霉素 1g/d口服 ,治疗 4周结节全部消退 ,留瘢痕和色素沉着 。

A 40 year old male patient suffered from horsebean size multiple nodules for 2 years Some nodules ulcerated and followed by fever for 10 days Histopathologically, epithelioid cell granuloma was observed at the periphery of skin appendages and in subcutaneous fat lobules USR(1∶32),RPR(1∶16),TPHA(1∶160) were positive After mezlocillin(4g/day) and azithromycin(1g/day) were given for 4 weeks All the nodules faded, and pigmentation or scar were remained