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羊口疮病毒研究进展 被引量:8

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摘要 羊口疮,又称为羊传染性脓疱皮炎(contagiousecthyma),由羊口疮病毒(Orfvirus,ORFV)引起,以口唇、舌、鼻、乳房等部位形成丘疹、水疱、脓疱和结成疣状结痂为特征。ORFV主要感染山羊和绵羊,也可感染人和其它动物。由于ORFV在世界范围内分布广泛,具有典型的动物传染性,因此成为动物痘病毒里仅次于牛痘病毒的研究最为广泛的病毒。本文根据近年来国内外的研究成果,从ORFV的病原学和羊口疮典型临床特点,ORFV基因组分析,引起的宿主免疫反应及其免疫逃避机制,对NF-κB通路的调节作用,临床诊断和治疗以及ORFV疫苗相关研究等几个方面进行介绍,并提出对ORFV未来研究的展望。1
出处 《国际病毒学杂志》 2012年第3期137-140,共4页 International Journal of Virology
基金 国家自然科学基金项目(31070138)
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参考文献23

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共引文献21

同被引文献45

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