已婚妇女人乳头瘤病毒感染流行病学调查

Epidemiological survey and risk factors of human papillomavirus infection status in married women

目的探讨已婚妇女人乳头瘤病毒(HPV)感染现况及影响因素。方法随机抽取三个社区1 155名已婚女性进行问卷调查、妇科检查和HPV DNA检测。结果 HPV感染率为12.99%,其中HR-HPV感染率为11.77%,显著高于LR-HPV感染,单一感染率显著高于复合感染(P<0.01)。不同年龄段及宫颈糜烂程度的HR-HPV感染率差异有统计学意义(P<0.05),性生活频率、使用避孕套及吸烟史与HR-HPV感染相关(P<0.05)。宫颈糜烂、性生活频率是HR-HPV感染危险因素,使用避孕套对HR-HPV感染有保护作用(P<0.05)。结论海宁市社区育龄期、围绝经期妇女HPV及HR-HPV感染率较高,与性接触及宫颈炎症有关,使用避孕套可降低HPV的感染率。

Objective To investigate human papillomavirus （HPV） infection status and influencing factors of married wom- en. Methods RandomLy selected 1155 married women in 3 communities conducted a questionnaire survey, gynecological examination and HPV DNA testing. Results HPV infection rate was 12.99%, of which HR-HPV infection rate of 11.77% was significantly higher than LR-HPV infection, the infection rate was significantly higher than a single composite infec- tion （P 〈 0.01 ）. Different ages and degrees of cervical erosion, HR-HPV infection was significantly （P 〈 0.05）. Sexual frequen- cy, condom use and smoking were related to HR-HPV infection （P 〈 0.05）. Cervical erosion, sexual frequency were the risk factors for HR-HPV infection, condoms use was protection factors for HR-HPV infection （P 〈 0.05）. Conclusion HR-HPV infection of reproductive age, perimenopausal women in Haining city community is high, and is related to sexual contact and cervical inflammation, condoms use could reduce the HVP infection rates.