脑卒中后抑郁的相关因素调查研究和分析

Research and analysis of relevant factors of depression after stroke

目的对脑卒中后抑郁的相关因素进行调查分析,旨在为日后积极采取早期预防及干预措施提供指导依据。方法选取2009年1月～2011年1月在我院确诊的脑卒中患者268例进行调查,其中出现PSD共100例,本研究对100例PSD患者的年龄、性别、文化程度、发病次数、病程、病变性质、病变部位等指标作为可能影响脑卒中后抑郁发生的相关因素进行调查分析。结果 268例脑卒中患者全部纳入调查研究,出现PSD共100例,发生率37.3%。脑卒中后抑郁与年龄、性别、文化程度、脑卒中的位置、合并基础疾病如高血压、糖尿病等,以及发生脑卒中的次数、脑卒中后抑郁的病程及合并症关系密切(P<0.05或P<0.01),而与脑卒中的性质关系不大(P>0.05)。结论脑卒中后抑郁为多种因素共同作用的结果,对其相关因素进行调查分析,可以为临床进行干预治疗提供有效的指导依据,从而进一步降低PSD的发病率、改善抑郁症状,提高患者的生活质量。

Objective To explore and analyze the relevant factors of depression after stroke, and to provide guidance basis for taking positive measunes for the future prevention and early intervention. Methods All 268 cases stroke patients were diagnosed in our hospital from January 2009 to January 2011 ,there were 100 cases PSD, the PSD study of 100 cases the patient＇s age, gender, education level, disease frequency, course of the disease, lesions, lesions and other indicators as may affect the occurrence of post-stroke depression-related factors as survey indicators were analyzed. Results All 268 stroke patients included in all research,there were 100 cases of PSD, the occurrence rate was 37.3%. Post-stroke depression and age, sex, education ,location of stroke, combined underlying diseases such as hypertension, diabetes ,stroke ,and the num- ber and duration of post-stroke depression and post-stroke complications were closely related（P 〈 0.05 or P 〈 0.01 ）,but little with the nature of stroke（P 〉 0.05）. Conclusion Post-stroke depression is the result of many factors, factors related to its investigation and analysis, can provide effective treatment of clinical interventions based on the guidance to further re- duce the incidence of PSD and improve depressive symptoms, improve the patient＇s quality of life.