肠内营养支持相关腹泻影响因素分析

Analysis of the influencing factor for enteral nutrition-related diarrhea

目的探讨肠内营养支持相关性腹泻的影响因素及预防对策。方法 120例患者行肠内营养支持治疗,按是否发生腹泻分为腹泻组和对照组,分析与腹泻相关的因素。结果腹泻组118例,对照组132例,两组年龄、病情程度、抗生素种类及应用抗酸剂、胃肠动力药、钾剂、益生菌、B族维生素比例之间差异有统计学意义(P<0.05)。抗生素种类、年龄及应用抗酸剂、胃肠动力药、钾剂为肠内营养患者腹泻的危险因素(P<0.05),应用益生菌、B族维生素为肠内营养患者腹泻的保护因素(P<0.05)。结论年龄及药物因素是导致肠内营养支持相关性腹泻的主要影响因素,临床尽量避免危险因素并应用可防止腹泻的药物。

Objective To analyze the influencing factor for enteral nutrition-related diarrhea. Methods All of 120 cases EEN were divided into diarrhea group and control group. Retrospectively analyzed the clinical data. Results Diarrhea group of 118 cases and control group of 132 eases. The age, illness degree, antibiotics kinds and the condition of antiacid, gastrointestinal dynamical medicine, potassic preparation, probiotics preparation and Vitamine B had significant difference between two groups （P 〈 0.05）. The age, antibiotics kinds and the condition of antiacid, gastrointestinal dynamical medicine and potassic preparation were the risk factor for enteral nutrition-related diarrhea （P 〈 0.05）. The probioties preparation, Vitamine B were the protective factors for enteral nutrition-related diarrhea （P 〈 0.05）. Conclusion Age and medicine factor are the most important influencing factor for enteral nutrition-related diarrhea. Should be cautious to avoid the risk factors and use the prevent diarrhea drug.