摘要
目的探讨加镁极化液治疗抗精神病药物急性中毒所致心肌损害的疗效。方法将我院78例此类患者分为两组,治疗组40例给予镁极化液,对照组38例给予磷酸肌酸钠,对比心肌酶指标和心电图改变。结果观察组治疗前后肌酸激酶(CK)、乳酸脱氢酶(LDH)、肌酸激酶MB同工酶(CK-MB)的降低幅度与对照组相比差异无统计学意义(P均>0.05)。观察组T波改变、室性早搏、传导阻滞、ST-T段下降的治疗有效率显著高于对照组,两组比较差异有统计学意义(P均<0.05)。结论运用加镁极化液治疗抗精神病药物急性中毒所致心肌损害疗效确切,可有效改善心电图和心肌酶指标,具有经济、有效、安全的优点。
Objective To explore the therapeutic efficacy of plus magnesium GIK in the treatment of myocardial damage caused by acute antipsychotic poisoning. Methods 78 patients with myocardial damage caused by acute antipsychotic poi- soning were divided into 2 groups： treatment group （n = 40） received plus magnesium GIK, while control group （n = 38） was given creatine phosphate sodium. Methods There were no significant differences in the change extent of Creatine kinase （CK）, Lactate dehydrogenase （LDH）, Creatine kinase MB isoenzyme （CK-MB） between treatment group and control group （P all 〉 0.05）. The treatment efficiency in T wave changes, premature ventricular contractions, block, ST-T segment de- pression of treatment group were significantly higher than those of control group, respectively （P all 〈 0.05）. Conclusion Plus magnesium GIK in the treatment of myocardial damage caused by acute antipsychotic poisoning shows significant therapeutic efficacy, and is superior to creatine phosphate sodium in antiarrhythmic.
出处
《中国现代医生》
2012年第16期84-85,共2页
China Modern Doctor
