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腹腔镜子宫切除术应用全麻复合硬膜外麻醉对患者应激反应及纤溶功能的影响 被引量:19

Effects of stress response and fibrinolytic function on laparoscopic hysterectomy with general anesthesia combined with epidural anesthesia
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摘要 目的探讨全麻复合硬膜外麻醉对腹腔镜下子宫切除术患者应激反应及纤溶功能的影响。方法 110例择期行腹腔镜下子宫切除术的患者随机分为A、B两组,A组采用全麻复合硬膜外麻醉,B组采用单纯全麻。结果两组麻醉5 min的AD、NA及血糖水平较麻醉前下降,术毕则显著升高,术毕及术后24 h B组的AD、NA及血糖水平均显著高于A组(P<0.05)。两组不同时点的各组DD、PAI-1及t-PA水平之间差异有统计学意义(P<0.05),麻醉5 min、术毕及术后24 h B组的DD、PAI-1及t-PA水平均显著高于A组(P<0.01)。结论全麻复合硬膜外麻醉更有效地抑制腹腔镜下子宫切除术患者的应激反应及纤溶亢进,有利于降低并发症的发生,是较为理想的腹腔镜手术麻醉方法。 Objective To investigate the effects of stress response and fibrinolytic function on laparoseopic hysterectomy with general anesthesia combined with epidural anesthesia. Methods A total of 110 cases of undergoing laparoscopic hys- terectomy were randomLy divided into A and B group,A group with general anesthesia combined with epidural anesthesia, B group with general anesthesia. Results The AD, NA and blood glucose levels of two groups in anesthesia 5 min were decreased, postoperative were significantly increased. AD,NA, and blood glucose of B group in postoperative and after 24 h were significantly higher than A group (P 〈 0.05).The DD ,PAI-1 and t-PA of two groups had significantly signinifi- cance,the DD and PAl-1 and t-PA of B group in anesthesia 5 min,postoperative and after 24 h were significantly higher A group (P 〈 0.01). Conclusion General anesthesia combined with epidural anesthesia is more effective to inhibit the stress response and hyperfibrinolysis in patients with laparoscopic hysterectomy,help to reduce the incidence of complications,is an ideal laparoscopic surgical anesthesia.
作者 游敬华
出处 《中国现代医生》 2012年第17期104-105,109,共3页 China Modern Doctor
关键词 腹腔镜 全身麻醉 硬膜外麻醉 应激 纤溶 Laparoscopy General anesthesia Epidural anesthesia Stress Fibrinolysis
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  • 1张大昕,赵蔚玲.PPAR-γ配体降低^(137)Cs照射诱导的PAI-1高表达[J].中华放射肿瘤学杂志,2005,14(4):357-361. 被引量:1
  • 2Fromes Y,Gaillard D,Ponzio O,et al.Reduction of the inflammatory response following coronary bypass grafting with total minimal extracorporeal circulation.Eur J Cardiothorac Surg,2002,22:527-533.
  • 3Mazzei V,Nasso G,Salamone G,et al.Prospective randomized comparison of coronary bypass grafting with minimal extracorporeal circulation system (MECC) versus off-pump coronary surgery.Circulation,2007,116:1761-1767.
  • 4Stalder M,Gygax E,Immer FF,et al.Minimized cardiopulmonary bypass combined with a smart suction device:the future of cardiopulmonary bypass? Heart Surg Forum,2007,10:E235-238.
  • 5Remadi JP,Marticho P,Butoi I,et al.Clinical experience with the mini-extracorporeal circulation system:an evolution or a revolution? Ann Thorac Surg,2004,77:2172-2175.
  • 6Remadi JP,Rakotoarivelo Z,Marticho P,et al.Prospective randomized study comparing coronary artery bypass grafting with the new mini-extracorporeal circulation Jostra System or with a standard card iopulmonary bypass.Am Heart J,2006,151:198.
  • 7Ranucci M,Isgrò G.Minimally invasive cardiopulmonary bypass:does it really change the outcome? Crit Care,2007,11:R45.
  • 8Rimpilainen R,Biancari F,Wistbacka JO,et al.Outcome after coronary artery bypass surgery with miniaturized versus conventional cardiopulmonary bypass.Perfusion,2008,23:361-367.
  • 9Koivisto SP,Wistbacka JO,Rimpilainen R,et al.Miniaturized versus conventional cardiopulmonary bypass in high-risk patients undergoing coronary artery bypass surgery.Perfusion,2010,25:65-70.
  • 10Miller BE,Levy JH.The inflammation response to cardiopulmonary bypass.J Cardiothorac Vasc Anesth,1997,11:355-366.

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