PiCCO监测指标与老年脓毒性休克患者预后的相关性研究

The correlation of PiCCO monitoring indicators and the prognosis of elderly septic shock patients

目的探讨PiCCO监测指标与老年脓毒性休克患者预后的相关性。方法分析36例脓毒性休克患者,采用常规集束化治疗,并行PiCCO监测,比较存活病例和死亡病例的首次PiCCO指标。结果 28 d存活17例,生存率为47.22%,死亡19例,死亡率为52.78%,存活组和死亡组APACHEⅡ的差异有统计学意义(P<0.05),入组时两组CI、EVLWI、PVPI之间差异有统计学意义(P<0.05),CI与EVLWI的ROC曲线下面积分别为0.853、0.743,两者水平评估患者预后差异有统计学意义(P<0.05)。结论 PiCCO监测能为评估脓毒性休克患者预后提供依据,其中CI和EVLWI水平与患者预后密切相关。

Objective To investigate the correlation of PiCCO monitoring indicators and the prognosis of elderly septic shock patients. Methods 36 cases of septic shock patients using conventional cluster treatment were analyzed, used PiCCO monitoring and compared the first time PiCCO indicators for survival and deaths cases. Results After 28 d, 17 cases of sur- vival, the survival rate was 47.22%, and 19 cases died, the mortality rate was 52.78%, the APACHE ]I difference between survival group and death group was statistically significant （P 〈 0.05）. The differences of CI, EVLWI and PVPI between two groups were statistically significant （P 〈 0.05）, the area under the ROC curve of CI and EVLWI were 0.853, 0.743, both the level of assessment of the patient prognosis were statistically significant （P 〈 0.05）. Conclusion PiCCO monitoring could pro- vide a basis for assessing the prognosis of patients with septic shock, the level of CI and EVLWI is closely related to the prognosis.