摘要
目的探讨慢性胃炎根除Hp患者临床症状、内镜表现及病理变化,明确根除Hp对慢性胃炎的疗效。方法对内镜诊断为慢性胃炎合并Hp阳性患者100例,分为Hp阳性耐药治疗组60例,Hp阳性耐药对照组40例。均以铝碳酸镁片1.0 g口服,3次/日,8周。8周后检测Hp,复查胃镜后评估消化道症状及胃镜改变。结果两组治疗前后症状总评分、内镜下糜烂改变有统计学意义(P<0.05)。Hp阳性耐药治疗组治疗前后症状评分差值为(3.42±1.25),显著高于Hp阳性耐药对照组(2.80±1.24)(P<0.05)。结论伴有Hp感染的慢性胃炎根除Hp有助于症状改善,在耐药患者Hp根除方案的选择上,序贯疗法的根除率优于四联疗法。
Objective To investigate whether H. pylori eradication has effects on dyspeptic symptoms, erosion and patholo- gy in patients with chronic gastritis infected with H. pylori. Methods One hundred patients with chronic gastritis were ran- domized into two groups including the treatment group（30 cases underwent a 10 day sequential therapy, 30cases received a 7-day quadruple therapy）and the control group （40 cases）. All cases receive magnesium sulphate therapy with oral for 8 weeks. Result There was significant difference found in dyspeptic symptoms, erosion, pathology compared with baseline（P 〈0. 05）. The decrease in symptom score of the treatment group was（3.33 ± 1.25）, significantly higher than that of the con- trol group （2.80 ± 1.24） （P 〈0. 05）. Conclusion Patients with chronic gastritis infected with H. pylori should receive erad- ication therapy early, sequential therapy is associated with better efficacy.
出处
《中国现代医生》
2012年第18期163-164,共2页
China Modern Doctor
关键词
序贯疗法
螺杆菌
幽门
胃炎
Sequential therapy
Helicobacter pylori
Gastritis
