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SCANNING AND ANALYSIS OF MISMATCH DISTRIBUTION ON HUMAN GENOME

SCANNING AND ANALYSIS OF MISMATCH DISTRIBUTION ON HUMAN GENOME
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摘要 The mismatch distribution is a good descriptive summary statistic that describes the phenomena of population genetics. This article scanned mismatch distribution on human genome with single nucleotide polymorphism (SNP) data from the International HapMap Project. It is found that the abnormal mismatch distribution could imply some special segments on some chromosomes. One of the segments, on chromosome 8, was proved as an inversion. Other special segments may also imply some special structure on chromo- somes, such as duplication. The conjectures of other segments still need further research.
出处 《International Journal of Biomathematics》 2012年第3期169-176,共8页 生物数学学报(英文版)
关键词 Population genetics mismatch distribution single nucleotide polymorphism(SNP). 基因组扫描 人类基因组 染色体异常 单核苷酸多态性 歧点 群体遗传学 汇总统计 计划数据
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