1-苯基-3-甲基-5-芳氧基-1H-吡唑-4-甲醛-O-[(2-氯吡啶-5-基)甲基]肟的合成与生物活性

Synthesis and Bioactivities of Novel 1-Phenyl-3-methyl-5-aryloxy-1H-pyrazole-4-carbaldehyde-O-[(2-chloropyridin-5-yl)methyl]oximes

利用1-苯基-3-甲基-5-芳氧基吡唑4-甲醛肟与2-氯-5-氯甲基吡啶发生缩合反应,合成了14个新型含吡啶环的吡唑肟醚衍生物.通过1H NMR,13C NMR和元素分析对所合成的化合物进行了结构表征.初步生物活性测试结果表明,在试验浓度下部分化合物具有一定的杀菌和植物生长调节活性.

Fourteen novel pyrazole oxime ether derivatives containing a 2-chloro-5-methyl pyridyl ring were synthesized by the reaction of 1-phenyl-3-methyl-5-aryloxy-1H-pyrazole-4-carbaldehyde oximes with 2-chloro-5-chloromethyl pyridine.The structures of all new compounds were confirmed by 1H NMR,13C NMR spectra and elemental analysis.Preliminary bioassay results indicated that some compounds exhibited certain fungicidal and plant growth regulatory activities.