肝癌患者围术期预防用抗菌药物情况分析

Analysis of Perioperative Prophylactic Application of Antimicrobial Drugs in Liver Cancer Patients

目的:了解我院肝癌患者围术期预防用抗菌药物情况。方法:调取我院2009-2011年肝癌患者的手术病历,每月随机抽取5份,分别对其预防用抗菌药物品种、用药时机、用药疗程等进行评价。结果:我院肝癌患者围术期预防用抗菌药物比例达70.9%(124/175);平均用药时间为4.3d;术前用药占49.2%(61/124),术中用药占38.7%(48/124),术后用药占12.1%(15/124);合理用药占64.3%,不合理用药占17.5%。结论:我院肝癌患者预防用药存在指征把握不严、用药种类不当及用药过度等现象,亟待改进。

OBJECTIVE： To investigate perioperative prophylactic application of antimicrobial drugs in liver cancer patients in our hospital. METHODS： 5 surgery medical records of liver cancer patients were randomly collected from our hospital each month during 2009 to 2011. The category of antimicrobial drugs for preventive use, medication timing, treatment course and other index were evaluated. RESULTS： The perioperative prophylactic application of antimicrobial drugs in liver cancer patients accounted for 70.9% in our hospital （124/175）, with average medication time of 4.3 d. The preoperative medication occupied 49.2% （61/124）, intraoperative medication 38.7% （48/124）, post-operative medication 12.1% （15/124）. Rational drug use accounted for 64.3%, and irrational drug use accounted for 17.5%. CONCLUSION： The prophylactic application of drugs in liver cancer patients in our hospi- tal has some problems in terms of grasping the indication of preventive medication, type of drug used and excessive drug use, which need to be improved.