我院2011年病原菌分布情况及耐药性分析

Analysis of Distribution and Drug Resistance of Pathogens in Our Hospital in 2011

目的:汇总我院2011年分离病原菌的构成及耐药性的动态变化。方法:采用回顾性分析方法,对我院2011年病原菌分布、构成及耐药性进行统计、汇总。结果:2011年分离检出的革兰阴性菌2690株(62.65%)中全部耐药的革兰阴性菌占1.33%,革兰阳性菌528株(12.30%),真菌1076株(25.06%);主要病原菌是大肠埃希菌(16.02%)、肺炎克雷伯菌(12.74%)、铜绿假单胞菌(11.29%)、鲍曼不动杆菌(9.41%)。革兰阳性菌对呋喃妥因高度敏感,革兰阴性菌对碳青霉烯类抗菌药物耐药性最低。结论:抗菌药物使用应加强药敏检测,合理选择抗菌药物。

OBJECTIVE： To summarize the composition and drug resistance change of bacterial isolates in our hospital in 2011. METHODS： By using retrospective analysis method, the distribution, composition and drug resistance of bacteria were sum- marized statistically in our hospital in 2011. RESULTS： 2 690 strains of Gram-negative bacteria were isolated and detected in 2011 （62.65%）, of which 1.33% of Gram-negative bacteria were completely drug-resistant; 528 strains were Gram-positive bacteria （12.30%） , 1 076 strains were fungi （25.06%） ; the main pathogens were Escherichia coli （16.02%） , Klebsiella pneumoniae （ 12.74% ）, Pseudomonas aeruginosa （ 11.29% ）, Acinetobacter baumannii （9.41% ）. Gram-positive bacteria were highly sensitive to nitrofurantoin, and Gram-negative bacteria showed the minimum resistance to carbon carbapenem antibiotics. CONCLUSION： We should enhance susceptibility test for antibiotics use and choose antibiotics reasonably.