糖化血红蛋白<7.0%的2型糖尿病患者动态血糖图谱分析

Glycemic Patterns and Excursions in HbA1c<7.0% Patients with Type 2 Diabetes Mellitus

为了观察糖化血红蛋白(HbA1c)<7.0%的2型糖尿病患者动态血糖变化情况,选择34例HbA1c<7.0%的2型糖尿病患者,行连续动态血糖监测(CGMS)后进行血糖图谱分析。结果显示,CGMS所记录的血糖值与指尖血糖值呈显著正相关(r=0.971,P<0.005)。血糖控制"良好"的糖尿病患者仍存在明显的餐后血糖过高现象,及夜间无症状性低血糖。血糖小于3.9mmol/L,大于8mmol/L和11.1mmol/L所占时间百分率分别为3.38%、32.44%和8.94%。由此可见,动态血糖监测能较详细地显示2型糖尿病患者血糖水平波动的特征,为拟定更加合理的治疗方案提供临床依据。

To reveal the glycemic excursions in HbA1c〈7.0% patients with type 2 diabetes mellitus. 34 patients with type 2 dia- betes （HbA1c〈7.0% ） participated in the study. The fluctuations of glucose levels in the participants were measured by a continuous glucose monitoring system （CGMS）. The CGMS values in this study were significantly correlated with capillary glucose （r=0. 971 ,P〈0. 005）. The ＂well-controlled＂ patients presented with obviously postprandial hyperglycemia and asymptomatic hypoglycemia. The time durations for blood glucose levels of 3.9 mmol/L, 7. 8 mmol/L and 11. 1 mmol/L were 3. 38%, 32.44 % and 8.94 %, respectively. In conclusion, the CGMS could provide information about the glycemic excursions and trends in detail in type 2 diabetes patients,which is important for choosing the optimal management regimen for the patients with type 2 diabetes mellitus.