茎花葱臭木化学成分的研究(英文)

Chemical Constituents from Dysoxylum cauliflorum(Meliaceae)

从茎花葱臭木种子中分离得到5个化合物,经理化与波谱分析鉴定为β-谷甾醇(1)、没食子酸乙酯(2)、胡萝卜苷(3)、1-O-β-D-吡喃葡萄糖基-(2S,3S,4R,8Z)-2-N-(2'-羟基二十四烷酰氨基)十八二氢鞘氨-8-烯(4)和2,3,2″,3″-四氢穗花杉双黄酮(5)。这5个化合物均首次从该植物中分离得到。其中化合物5进行细胞毒活性测试,没有显示抑制活性。

Five compounds were isolated from the seeds of Dysoxylum cauliflorum and their structures were elucidated as β-sitosterol（1）,ethyl gallate（2）,daucosterol（3）,1-O-β-D-glucopyranosyl-（2S,3S,4R,8Z）-2-N-（2′-hydroxytetracosanoyl） octadecasphinga-8-ene（4）,and 2,3,2″,3″-tetrahydroamentoflavone（5）.All of these compounds were isolated from this plant for the first time.Compound 5 was evaluated for cytotoxicity against five human cancer cell lines but showed no inhibitory activities.