阻塞性睡眠呼吸暂停低通气综合征患者性别差异分析

Analysis the differences between genders in patients with obstructive sleep apnea-hypopnea syndrome

目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者临床及多导睡眠图(PSG)监测性别间差异。方法比较201例OSAHS患者中不同性别的呼吸暂停低通气指数(AHI)、最低血氧饱和度(LSpO2)、体质指数(BMI),AHI和LSpO2不同分级间以及呼吸事件形式。结果男性患者平均年龄(46.2±11.7)岁小于女性(55.4±7.9)岁,男性患者AHI(37.8±25.8)次/h大于女性(27.9±20.4)次/h,男性患者LSpO2(77.0±10.9)%低于女性(81.4±5.4)%,差异均具有统计学意义。男女BMI间差异无统计学意义。男女患者在AHI和LSpO2不同分级间差异无统计学意义。呼吸事件形式上男性患者以呼吸暂停为主,女性以低通气为主,差异具有统计学意义。结论男性OSAHS患者年龄小于女性,病情较女性重,以呼吸暂停表现为主。

Objective To study the differences between genders in clinic and polysomnography in patients with obstructive sleep apnea-hypopnea syndrome.Methods To compare the differences between genders in apnea hypopnea index（AHI）,the lowest saturation of blood oxygen（LSpO_2）,body mass index（BMI）,and different degrees in AHI and the lowest saturation of blood oxygen,as well as the performance of the respiratory events in 201 patients with OSAHS.Result The mean age of male patients was 46.2±11.7 years,that was younger than that of female patients which was 55.4±7.9;the difference was considered significant.The average AHI of male patients was 37.8±25.8/h,that was higher than that of female patients which was 27.9±20.4/h;the difference was considered significant.The difference had no significance in the mean BMI and different degree in AHI and the lowest saturation of blood oxygen.Male patients mainly presented apnea,and female patients mainly presented hypopnea,the difference was considered significant.Conclusion Male patients are younger than the females,and the pathogenetic condition more severe,mainly in appearance of apnea.