老年高血压患者动态血压变化与颈动脉硬化的关系

The relationship between elder patients with hypertension ambulatoyy blood pressure changes and carotid atherosclerosis

目的探讨老年高血压病患者动态血压参数对颈动脉内膜中层厚度的影响。方法老年高血压患者160例经颈动脉超声检查分为颈动脉硬化组(CAS)及颈动脉正常组(CAN)。将两组动态血压检测结果进行组间对照,并对相关数据与颈动脉硬化进行相关性分析。结果①CAS组白天、夜间及24h平均收缩压、舒张压、脉压水平均明显高于CAN组,两组参数比较差异有统计学意义(P<0.05);②CAS组血压昼夜节律变化消失或减弱者较CAN组明显增多(P<0.05)。结论老年高血压病动态血压参数对颈动脉内膜中层增厚有显著影响,且老年高血压病合并颈动脉硬化患者存在着明确的异常昼夜血压节律。

Objective To investigate the influence of elder patients with hypertension ambulatory blood pressure changes parameters on the intima-media thikness of carotid artery.Methods 160 cases of elder patients with hypertension were randomly divided into carotid atherosclerosis group（CAS） and control group（CAN）.Ambulatory blood pressure change of two groups were compared.Correlation amalyse was performed between carotid atherosclerosis and related data.Results ①Day night and 24 hour average systolic blood pressure,higher than CAN group.There was a statistical signiticance in two groups（P〈0.05）.②The patients with blood pressure diurnal rhythms change disappear and decrease were significantly in creased in CAS group than CSN group.Conclusion There was a significantly influence of elder patients with hypertension ambulatory blood pressure change parameters on the intima-media thickness of carotid artery.There was a definite and abnormal blood pressure diurnal rhythms in patients with the hyper tension and carotid atherosclerosis.