出血性脑卒中后全身炎症反应综合征72例临床分析

Clinical analysis of 72 cases of hemorrhagic stroke systemic inflammatory response syndrome

目的探讨全身炎症反应综合征(SIRS)在出血性脑卒中中的发生情况和临床特点。方法回顾性分析2008～2010年收治的110例出血性脑卒中患者的完整临床资料,按发病后3d内SIRS发生情况分为普通组和SIRS组,分析两组临床特点,比较两组血小板计数、C-反应蛋白水平、病死率情况。结果 SIRS组中桥脑出血占13%,大量出血占91%,蛛网膜下隙出血占7%,而普通组分别为5%、6%和2%。SIRS组血小板计数低于普通组,C-反应蛋白水平高于普通组,病死率高于普通组,差异有统计学意义(P<0.05)。结论 SIRS常有血小板降低,C-反应蛋白明显增高;大量出血和桥脑部位出血、蛛网膜下隙出血患者易发生SIRS,患者病死率高。

Objective To investigate the systemic inflammatory response syndrome in the incidence of hemorrhagic stroke and the clinical characteristics.Methods A retrospective analysis of 2008 to 2010 treated 110 cases of hemorrhagic stroke in patients with complete clinical data,according to SIRS occurred within 3 days after onset were divided into normal group and the SIRS group,the clinical characteristics of the two groups were compared platelet count,C-reactive protein level,the case fatality rate.Results In SIRS group,Pontine hemorrhage and heavy bleeding rate were 13% and 91%,subarachnoid hemorrhage 7% while the normal group were 5% 、6%and 2%.SIRS group platelet count less than normal group,C-reactive protein level higher than the normal group,mortality was higher than the normal group,the difference was statistically significant（P〈0.05）.Conclusion SIRS platelets often cut down,C-reactive protein was significantly higher in SIRS,heavy bleeding,pontine hemorrhage and subarachnoid hemorrhage often occurs SIRS,patients with high mortality.