2006—2010年国家级布鲁杆菌病监测点监测结果分析

Brucellosis from 2006 to 2010： an analysis of surveillance results at the national surveillance spots

目的分析2006—2010年国家级布鲁杆菌病监测点监测结果，掌握全国布鲁杆菌病流行现状，为评价监测工作质量、制订全国布鲁杆菌病防治策略和措施提供科学依据。方法对2006—2010年《中国重点传染病和病媒生物监测报告》和《中国疾病监测信息报告管理系统》中布鲁杆菌病监测数据按常规监测和监测点监测进行分类汇总、描述分析。采用二阶段聚类统计分析进行监测点分类。结果2006—2010年全国常规疫情监测报告发病率从2006年的1．55／10万逐年上升至2010年的2．62／10万，报告病例主要集中在内蒙古、山西省、黑龙江省等地区，时间集中在3—8月，占79．87％（114265／143064），以青壮年、男性、农牧民为主。2006—2010年国家级布鲁杆菌病监测点监测，共流行病学调查217648人，血清学检查61905人，阳性率为19．66％（12169／61905），其中新发病例10318例；各监测点血检阳性率以内蒙古扎兰屯最高，为41．19％（2757／6694）；病原学培养总出菌率为2．49％（29／1165）；牛、羊血清学检查阳性率分别为1．07％（2355／219352）、0．93％（2766／296176）：聚类分析将国家级布鲁杆菌病监测点分为4类。结论我国布鲁杆菌病人间疫情持续上升，国家级监测点监测工作贡献突出，但血清学与病原学监测数量和质量有待提高，可据此分类结果对不同类别的监测点进行分类管理。为提高卫生资源的利用率和布鲁杆菌病防控工作水平提供一定依据。

Objective To analyze the surveillance results at the national surveillance spots of brucellosis from 2006 to 2010, to know the epidemic status of national brucellosis, and to provide scientific evidences for evaluating of surveillance quality and formulating of surveillance strategies and measures. Methods The brucellosis surveillance data collected from the Surveillance Reports of Major Infectious Diseases and Vector- Biological Monitoring Report in China from 2006 to 2010, and the National Diseases Surveillance Information Management System were classified and analyzed using two stage clustering statistical analysis. Results According to national routine surveillance, the incidence of brucellosis increased from 1.55 per 100 000 in 2006 to 2.62 per 100 000 in 2010. Reported brucellosis cases were mainly in Inner Mongolia, Shanxi, Heilongjiang and other regions, and reported time was from March to August, which accounting for 79.87% （114 265/143 064）. The brucellosis cases were mainly youth, male, farmers and herdsman. In the national surveillance spots of the brucellosis, 217 648 eases received epidemic survey, of which 61 905 eases received serological test, the positive rate was 19.66% （12 169/61 905）, and 10 318 new cases were found;, the highest positive rate of serological test was 41.19%（2757/6694） which was found in Zhalantun of Inner Mongolia; the detection rate of pathogen culture was 2.49% （29/1165）; the positive rates of serological test in cattle and sheep were 1.07% （2355/219 352） and 0.93% （2766/296 176）, respectively. The surveillance spots were classified into four grades according to cluster analysis. Conclusions The epidemic continues to rise in human surveillance spots of brucellosis. Although national surveillance spots play an important role in the surveillance of brucellosis, the quality and quantity of surveillance work of national brucellosis surveillance spots should be improved, different management measures should be taken in different surveillance spots according to classified results of the cluster analysis. This study provides some basis to improve the utilization of health resources and the level of BruceUa disease prevention and control work.