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肿瘤免疫耐受——肿瘤细胞的免疫学特性 被引量:3

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摘要 肿瘤可以看作是一种免疫性疾病,即病理性的免疫耐受疾病。正常的(生理性的)免疫耐受是人体重要的防御和维护机制,能保证免疫杀伤功能不伤害自身,也就是不会发生冤假错案。例如,免疫耐受可以保证免疫系统不识别自身细胞和抗原、防御超敏性免疫反应及自身免疫性疾病的发生、保护自身生殖细胞和成体干细胞不受周围免疫系统的干扰、保护胎儿不受母体免疫系统排斥等。病理性的免疫耐受是病原体(例如肝炎病毒)为了长期保持在宿主体内的感染状态或肿瘤细胞为了逃逸免疫的监督,
作者 郭礼和
出处 《中国细胞生物学学报》 CAS CSCD 北大核心 2012年第7期732-734,共3页 Chinese Journal of Cell Biology
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