灵芝、裂褶菌多糖体外抗氧化活性的实验研究

A Study on Ganoderma Lucidum,Schizophyllum Commune Polysaccharide in Vitro Antioxidant Activity

目的:研究灵芝多糖和裂褶菌多糖体外抗氧化活性;方法:通过超氧阴离子自由基清除实验、还原力测定、小鼠红细胞氧化损伤和肝线粒体肿胀的实验,比较两种真菌多糖抗氧化活性的差异;结果:两种多糖对超氧阴离子自由基和羟基自由基引起的氧化损伤均有良好的抑制作用;结论:灵芝多糖和裂褶菌多糖都具有较强的体外抗氧化活性.

The present study aims at the vitro antioxidant activity of Ganoderma Lucidum polysaccharide and Schizophyllum Commune polysaccharide. Based on the superoxide anion free radical scavenging assays, the determination of reducing power, the oxidative damage to the red blood cell of the mouse and the liver mitochondrial swelling experiment on the mouse, the difference of antioxidant activities between Ganoderma Lucidum polysaccharide and Schizophyllum Commune polysaccharide was compared. The results show that both of the polysaccharides have good suppressive effects on the oxidative damage affected by superoxide anion radicals and hydroxyl free radicals. It is concluded that both of the polysaccharides have a strong antioxidant activity.