急性胰腺炎病人血清G-CSF和CRP的变化

The variance of levels of serum G-CSF and CRP in patients with acute pancreatitis

目的 测定急性胰腺炎 (AP)病人血清粒细胞集落刺激因子 (G -CSF)和C -反应蛋白 (CRP)水平 ,并探讨其临床意义。方法 对 41例AP病人和 40例正常对照组利用双抗体夹心ELISA法测定血清G -CSF ,快速免疫消浊比浊法测定CRP。结果 AP病人血清G -CSF和CRP水平较正常对照组明显增高 ,其中重症急性胰腺炎 (SAP)又较轻症急性胰腺炎 (MAP)病人血清G -CSF和CRP水平增高 (P <0 0 5 )。血清G -CSF和CRP的变化和病情变化一致。结论 血清中G -CSF可能与AP的严重程度有关 ,在临床上检测血清G

Objective To study the variance and clinic significance of levels of serum granulocyte colony-stimulating factor(G-CSF) and C-reactive protein(CRP) in patients with acute pancreatitis(AP).Methods G-CSF and CRP levels in 41 cases with AP and 40 cases normal control were analysed.Results G-CSF and CRP levels were higher in sera wth severe acute pancreatitis(SAP) and mild acute pancreatitis patients(MAP) than that with normal control group(P<0 05);and G-CSF and CRP levels in SAP group increased significantly in compare with that in MAP group(P<0 05).Changes in G-CSF and CRP coincided with the condition of the patients.Conclusion Levels of G-CSF and CRP in sera of AP patients may le closely related to the severity of the disease .The combination of serum G-CSF and CRP assays may be usod to judge the severely of AP and the effectiveness of The treatment.