长沙地区疱疹病毒性脑炎的病原研究

Study on the etiology of herpes viral encephalitis in Changsha area

目的 :探讨长沙地区病毒性脑炎与疱疹病毒感染的关系。方法 :应用间接免疫荧光技术 (IFA)检测病毒性脑炎患者脑脊液或血清中疱疹病毒特异性IgG ,IgM。结果 :92 1例病毒性脑炎患者中有 1 33例 (1 4 4% )诊断为单纯疱疹病毒性脑炎 ,1 0岁以下年龄为发病高峰 ,9例 (0 98% )诊断为巨细胞病毒性脑炎 ,1 2例 (1 3 % )为水痘 带状疱疹病毒性脑炎。结论 :长沙地区疱疹病毒性脑炎病原以单纯疱疹病毒最常见 ;

Objective: To study the relationship between herpes viral infection and viral encephalitis. Methods: The cerebral spinal fluid(CSF) and sera of the patients with viral encephalitis were detected for herpes virus specific IgG and IgM with indirect fluorescent antibody assay (IFA). Results: One hundred and thirty three(14.4%) cases of 921 patients with viral encephalitis were diagnosed as herpes simplex viral encephalitis, of which the maximum morbidity is under the age of 10, 9(0.98%) cases as cytomegaloviral encephalitis and 12(1.3%) cases as varicella zoster viral encephalitis. Conclusion: Herpes simplex viruses are the common causative agents of viral encephalitis in Changsha area, and IFA is valuable for the diagnosis of herpes viral encephalitis. [