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右美托咪定用于眼科手术病人术中镇静的临床观察 被引量:11

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摘要 目的探讨右美托咪定用于局部麻醉下眼科手术病人术中镇静的可行性。方法 ASAⅠ~Ⅱ级择期行眼科手术病人45例,随机分为D1组(右美托咪定0.8μg.kg-1)、D2组(右美托咪定1.2μg.kg-1)和C组(对照组),每组15例。所有患者均用0.375%布比卡因行球后神经阻滞。术中连续观察SBP、DBP、HR、SpO2和OAA/S评分,以及并发症及不良反应发生情况。结果给予右美托咪定后10、30及60 minD1、D2组OAA/S评分和SBP、DBP及HR均较术前有明显下降(P<0.05,P<0.01),组间比较有明显差异(P<0.05),手术结束时逐渐恢复接近术前水平。所有病人手术全程SpO2无明显变化,术中未出现躁动、嗜睡及呼之不应等麻醉并发症。结论 0.8~1.2μg.kg-1右美托咪定可安全用于眼科局麻手术中的镇静。
出处 《安徽医药》 CAS 2012年第7期1014-1015,共2页 Anhui Medical and Pharmaceutical Journal
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共引文献118

同被引文献110

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