飞秒激光制瓣LASIK术中发生前房气泡51眼临床分析

An analysis of anterior chamber bubbles in fifty-one eyes during corneal flap creation withfemtosecond lase~

目的探讨飞秒激光制作角膜瓣导致前房气泡的原因。方法回顾性病例对照研究。2009年7月至2010年6月接受飞秒激光制瓣的准分子激光原位角膜磨镶术（LASIK）患者1034例（2058眼），其中发生前房气泡的共48例（51眼）设为观察组，未发生前房气泡的2007眼为对照组，分析前房气泡发生的原因。统计学处理采用成组t检验。结果所有患者手术顺利，术后裸眼视力达到或超过术前矫正视力；观察组角膜直径较对照组小，差异有统计学意义（担一9．21，P〈0．05）；观察组角膜厚度、角膜曲率和Kappa角与对照组比较差异无统计学意义。结论在瞳孑L较大及精确的眼球跟踪系统下．飞秒激光制瓣时产生的前房气泡并不会对患者的术后视力产生影响；对于角膜直径较小的患者，应适当缩小角膜瓣直径．以避免前房气泡的发生。

Objective To analyze the formation of anterior chamber bubbles during corneal flap creation in myopic patients who underwent laser-in-situ keratomilusis （LASIK） using the IntraLase femtosecond laser. Methods It was a restrospeetive case control study. One thousand thirty-four patients （2057 eyes） who underwent LASIK using the IntraLase femtoseeond laser were enrolled in this study. Anterior chamber gas bubbles were noted in study group （51 eyes） with no anterior chamber gas bubbles in the other 2007 eyes （control group）. The causes of anterior chamber bubble formation were analyzed. The date were analyzed by independent samples t test. Results Flap creation was successful and myopic ablation was uneventful. The corneal diameter in the study group was smaller than that in the control group （t=-9.21, P〈O.05）, but there were no significant differences between the two groups in other corneal parameters. Conclusion With a larger pupil and precise tracking, anterior chamber bubbles has no effect on postoperative visual acuity. To avoid the formation of anterior chamber bubbles during corneal flap creation, we would tighten the flap diameter in smaller corneas.