摘要
代谢组学是研究生物体在生物体基因组、生物体蛋白质组和生物体所处环境相互作用下代谢情况的一门系统生物学。肝细胞癌的发生发展必然带来机体代谢改变,代谢组学能"全景式"揭示肝细胞癌发生发展差异代谢物水平及其相互关系,为肝细胞癌的临床诊断和治疗提供思路。本文就近年来代谢组学在肝细胞癌研究中的应用作一综述。
Metabolomics is a systemic biology for study on organic metabolism status under interaction of the genome, pro- teome and survival environment of organisms. The development of hepatocellular carcinoma wiU inevitably bring about the change of metabolism. Metabolomics may reveal differential metabolites and their relationship panoramically and provide an idea for the clinical diagnosis and treatment of hepatocellular carcinoma. The application of metabolomics in study on hepatocellular carcinoma in recent year is reviewed in this paper.
出处
《中国生物制品学杂志》
CAS
CSCD
2012年第7期929-931,共3页
Chinese Journal of Biologicals
基金
重庆市教委2011年自然科学资助项目(KJ111802)
关键词
代谢组学
癌
肝细胞
代谢物
Metabolomics
Carcinoma, hepatocellular
Metabolite
